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What Is a Microsatellite: A Computational and Experimental Definition Based upon Repeat Mutational Behavior at A/T and GT/AC Repeats

Microsatellites are abundant in eukaryotic genomes and have high rates of strand slippage-induced repeat number alterations. They are popular genetic markers, and their mutations are associated with numerous neurological diseases. However, the minimal number of repeats required to constitute a micro...

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Detalles Bibliográficos
Autores principales: Kelkar, Yogeshwar D., Strubczewski, Noelle, Hile, Suzanne E., Chiaromonte, Francesca, Eckert, Kristin A., Makova, Kateryna D.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2940325/
https://www.ncbi.nlm.nih.gov/pubmed/20668018
http://dx.doi.org/10.1093/gbe/evq046