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Activation of the Hedgehog pathway in pilocytic astrocytomas

Pilocytic astrocytoma is commonly viewed as a benign lesion. However, disease onset is most prevalent in the first two decades of life, and children are often left with residual or recurrent disease and significant morbidity. The Hedgehog (Hh) pathway regulates the growth of higher WHO grade gliomas...

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Detalles Bibliográficos
Autores principales: Rush, Sarah Z., Abel, Ty W., Valadez, Juan G., Pearson, Matthew, Cooper, Michael K.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2940682/
https://www.ncbi.nlm.nih.gov/pubmed/20223881
http://dx.doi.org/10.1093/neuonc/noq026