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Activation of the Hedgehog pathway in pilocytic astrocytomas
Pilocytic astrocytoma is commonly viewed as a benign lesion. However, disease onset is most prevalent in the first two decades of life, and children are often left with residual or recurrent disease and significant morbidity. The Hedgehog (Hh) pathway regulates the growth of higher WHO grade gliomas...
Autores principales: | Rush, Sarah Z., Abel, Ty W., Valadez, Juan G., Pearson, Matthew, Cooper, Michael K. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2940682/ https://www.ncbi.nlm.nih.gov/pubmed/20223881 http://dx.doi.org/10.1093/neuonc/noq026 |
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