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Thermodynamics-Based Models of Transcriptional Regulation by Enhancers: The Roles of Synergistic Activation, Cooperative Binding and Short-Range Repression

Quantitative models of cis-regulatory activity have the potential to improve our mechanistic understanding of transcriptional regulation. However, the few models available today have been based on simplistic assumptions about the sequences being modeled, or heuristic approximations of the underlying...

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Detalles Bibliográficos
Autores principales: He, Xin, Samee, Md. Abul Hassan, Blatti, Charles, Sinha, Saurabh
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2940721/
https://www.ncbi.nlm.nih.gov/pubmed/20862354
http://dx.doi.org/10.1371/journal.pcbi.1000935