Analysis of Population Structure: A Unifying Framework and Novel Methods Based on Sparse Factor Analysis

We consider the statistical analysis of population structure using genetic data. We show how the two most widely used approaches to modeling population structure, admixture-based models and principal components analysis (PCA), can be viewed within a single unifying framework of matrix factorization....

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Detalles Bibliográficos
Autores principales: Engelhardt, Barbara E., Stephens, Matthew
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2940725/
https://www.ncbi.nlm.nih.gov/pubmed/20862358
http://dx.doi.org/10.1371/journal.pgen.1001117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2940725/
https://www.ncbi.nlm.nih.gov/pubmed/20862358
http://dx.doi.org/10.1371/journal.pgen.1001117

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