Validation and use of microdialysis for determination of pharmacokinetic properties of the chemotherapeutic agent mitomycin C - an experimental study

BACKGROUND: Mitomycin C is a chemotherapeutic agent used in the treatment of peritoneal surface malignancies, administered as hyperthermic intraperitoneal chemotherapy after cytoreductive surgery. Pharmacokinetic studies have been based on analyses of blood, urine and abdominal perfusate, but actual...

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Detalles Bibliográficos
Autores principales: Sørensen, Olaf, Andersen, Anders, Olsen, Harald, Alexandr, Kristian, Ekstrøm, Per Olaf, Giercksky, Karl-Erik, Flatmark, Kjersti
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2940807/
https://www.ncbi.nlm.nih.gov/pubmed/20809961
http://dx.doi.org/10.1186/1471-2407-10-469

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2940807/
https://www.ncbi.nlm.nih.gov/pubmed/20809961
http://dx.doi.org/10.1186/1471-2407-10-469

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