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Validation and use of microdialysis for determination of pharmacokinetic properties of the chemotherapeutic agent mitomycin C - an experimental study
BACKGROUND: Mitomycin C is a chemotherapeutic agent used in the treatment of peritoneal surface malignancies, administered as hyperthermic intraperitoneal chemotherapy after cytoreductive surgery. Pharmacokinetic studies have been based on analyses of blood, urine and abdominal perfusate, but actual...
Autores principales: | Sørensen, Olaf, Andersen, Anders, Olsen, Harald, Alexandr, Kristian, Ekstrøm, Per Olaf, Giercksky, Karl-Erik, Flatmark, Kjersti |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2940807/ https://www.ncbi.nlm.nih.gov/pubmed/20809961 http://dx.doi.org/10.1186/1471-2407-10-469 |
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