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Deletion of Running-Induced Hippocampal Neurogenesis by Irradiation Prevents Development of an Anxious Phenotype in Mice

Recent evidence postulates a role of hippocampal neurogenesis in anxiety behavior. Here we report that elevated levels of neurogenesis elicit increased anxiety in rodents. Mice performing voluntary wheel running displayed both highly elevated levels of neurogenesis and increased anxiety in three dif...

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Detalles Bibliográficos
Autores principales: Fuss, Johannes, Ben Abdallah, Nada M. B., Hensley, Frank W., Weber, Klaus-Josef, Hellweg, Rainer, Gass, Peter
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2940841/
https://www.ncbi.nlm.nih.gov/pubmed/20862278
http://dx.doi.org/10.1371/journal.pone.0012769