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Crystal Structure of the RNA Recognition Motif of Yeast Translation Initiation Factor eIF3b Reveals Differences to Human eIF3b

BACKGROUND: The multi-subunit eukaryotic initiation factor3 (eIF3) plays a central role in the initiation step of protein synthesis in eukaryotes. One of its large subunits, eIF3b, serves as a scaffold within eIF3 as it interacts with several other subunits. It harbors an RNA Recognition Motif (RRM)...

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Detalles Bibliográficos
Autores principales: Khoshnevis, Sohail, Neumann, Piotr, Ficner, Ralf
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2940854/
https://www.ncbi.nlm.nih.gov/pubmed/20862284
http://dx.doi.org/10.1371/journal.pone.0012784