Anti-folate drug resistance in Africa: meta-analysis of reported dihydrofolate reductase (dhfr) and dihydropteroate synthase (dhps) mutant genotype frequencies in African Plasmodium falciparum parasite populations

BACKGROUND: Mutations in the dihydrofolate reductase (dhfr) and dihydropteroate synthase (dhps) genes of Plasmodium falciparum are associated with resistance to anti-folate drugs, most notably sulphadoxine-pyrimethamine (SP). Molecular studies document the prevalence of these mutations in parasite p...

Descripción completa

Detalles Bibliográficos
Autores principales: Sridaran, Sankar, McClintock, Shannon K, Syphard, Luke M, Herman, Karen M, Barnwell, John W, Udhayakumar, Venkatachalam
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2940896/
https://www.ncbi.nlm.nih.gov/pubmed/20799995
http://dx.doi.org/10.1186/1475-2875-9-247

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2940896/
https://www.ncbi.nlm.nih.gov/pubmed/20799995
http://dx.doi.org/10.1186/1475-2875-9-247

Ejemplares similares