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Heat shock transcription factor HSF1 plays a critical role in HER2-induced cellular transformation and tumorigenesis

The heat shock transcription factor HSF1 was recently demonstrated to play a key role in the development of tumors associated with activation of Ras or inactivation of p53. Here we show that HSF1 is required for cell transformation and tumorigenesis induced by HER2 oncogene responsible for aggressiv...

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Detalles Bibliográficos
Autores principales: Meng, Le, Gabai, Vladimir L., Sherman, Michael Y.
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2940982/
https://www.ncbi.nlm.nih.gov/pubmed/20622894
http://dx.doi.org/10.1038/onc.2010.277