Cargando…

Membrane Potential Depolarization as a Triggering Mechanism for Vpu-Mediated HIV-1 Release

Vpu, a component unique to HIV-1, greatly enhances the efficiency of viral particle release by unclear mechanisms. This Vpu function is intrinsically linked to its channel-like structure, which enables it to interfere with homologous transmembrane structures in infected cells. Because Vpu interacts...

Descripción completa

Detalles Bibliográficos
Autores principales: Hsu, Kate, Han, Jin, Shinlapawittayatorn, Krekwit, Deschenes, Isabelle, Marbán, Eduardo
Formato: Texto
Lenguaje:English
Publicado: The Biophysical Society 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2941015/
https://www.ncbi.nlm.nih.gov/pubmed/20858415
http://dx.doi.org/10.1016/j.bpj.2010.07.027