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Membrane Potential Depolarization as a Triggering Mechanism for Vpu-Mediated HIV-1 Release
Vpu, a component unique to HIV-1, greatly enhances the efficiency of viral particle release by unclear mechanisms. This Vpu function is intrinsically linked to its channel-like structure, which enables it to interfere with homologous transmembrane structures in infected cells. Because Vpu interacts...
Autores principales: | Hsu, Kate, Han, Jin, Shinlapawittayatorn, Krekwit, Deschenes, Isabelle, Marbán, Eduardo |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Biophysical Society
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2941015/ https://www.ncbi.nlm.nih.gov/pubmed/20858415 http://dx.doi.org/10.1016/j.bpj.2010.07.027 |
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