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Theoretical Formulation of Principal Components Analysis to Detect and Correct for Population Stratification

The Eigenstrat method, based on principal components analysis (PCA), is commonly used both to quantify population relationships in population genetics and to correct for population stratification in genome-wide association studies. However, it can be difficult to make appropriate inference about pop...

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Detalles Bibliográficos
Autores principales: Ma, Jianzhong, Amos, Christopher I.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2941459/
https://www.ncbi.nlm.nih.gov/pubmed/20862251
http://dx.doi.org/10.1371/journal.pone.0012510