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Sub-Nanoscale Surface Ruggedness Provides a Water-Tight Seal for Exposed Regions in Soluble Protein Structure

Soluble proteins must maintain backbone hydrogen bonds (BHBs) water-tight to ensure structural integrity. This protection is often achieved by burying the BHBs or wrapping them through intermolecular associations. On the other hand, water has low coordination resilience, with loss of hydrogen-bondin...

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Detalles Bibliográficos
Autores principales: Schulz, Erica, Frechero, Marisa, Appignanesi, Gustavo, Fernández, Ariel
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2941462/
https://www.ncbi.nlm.nih.gov/pubmed/20862253
http://dx.doi.org/10.1371/journal.pone.0012844