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Sub-Nanoscale Surface Ruggedness Provides a Water-Tight Seal for Exposed Regions in Soluble Protein Structure
Soluble proteins must maintain backbone hydrogen bonds (BHBs) water-tight to ensure structural integrity. This protection is often achieved by burying the BHBs or wrapping them through intermolecular associations. On the other hand, water has low coordination resilience, with loss of hydrogen-bondin...
Autores principales: | Schulz, Erica, Frechero, Marisa, Appignanesi, Gustavo, Fernández, Ariel |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2941462/ https://www.ncbi.nlm.nih.gov/pubmed/20862253 http://dx.doi.org/10.1371/journal.pone.0012844 |
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