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Bone Is Not Essential for Osteoclast Activation

BACKGROUND: The mechanism whereby bone activates resorptive behavior in osteoclasts, the cells that resorb bone, is unknown. It is known that α(v)β(3) ligands are important, because blockade of α(v)β(3) receptor signaling inhibits bone resorption, but this might be through inhibition of adhesion or...

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Detalles Bibliográficos
Autores principales: Fuller, Karen, Ross, Jade L., Szewczyk, Kinga A., Moss, Raymond, Chambers, Tim J.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2941467/
https://www.ncbi.nlm.nih.gov/pubmed/20862258
http://dx.doi.org/10.1371/journal.pone.0012837