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Identification of tumor-associated cassette exons in human cancer through EST-based computational prediction and experimental validation

BACKGROUND: Many evidences report that alternative splicing, the mechanism which produces mRNAs and proteins with different structures and functions from the same gene, is altered in cancer cells. Thus, the identification and characterization of cancer-specific splice variants may give large impulse...

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Detalles Bibliográficos
Autores principales: Valletti, Alessio, Anselmo, Anna, Mangiulli, Marina, Boria, Ilenia, Mignone, Flavio, Merla, Giuseppe, D'Angelo, Vincenzo, Tullo, Apollonia, Sbisà, Elisabetta, D'Erchia, Anna Maria, Pesole, Graziano
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2941758/
https://www.ncbi.nlm.nih.gov/pubmed/20813049
http://dx.doi.org/10.1186/1476-4598-9-230