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Identification of tumor-associated cassette exons in human cancer through EST-based computational prediction and experimental validation
BACKGROUND: Many evidences report that alternative splicing, the mechanism which produces mRNAs and proteins with different structures and functions from the same gene, is altered in cancer cells. Thus, the identification and characterization of cancer-specific splice variants may give large impulse...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2941758/ https://www.ncbi.nlm.nih.gov/pubmed/20813049 http://dx.doi.org/10.1186/1476-4598-9-230 |