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Notch and EGFR pathway interaction regulates neural stem cell number and self-renewal
Specialized cellular microenvironments, or “niches,” modulate stem cell properties, including cell number, self-renewal and fate decisions1,2. In the adult brain, niches that maintain a source of neural stem cells (NSCs) and neural progenitor cells (NPCs) are the subventricular zone (SVZ) of the lat...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2941915/ https://www.ncbi.nlm.nih.gov/pubmed/20844536 http://dx.doi.org/10.1038/nature09347 |