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Notch and EGFR pathway interaction regulates neural stem cell number and self-renewal

Specialized cellular microenvironments, or “niches,” modulate stem cell properties, including cell number, self-renewal and fate decisions1,2. In the adult brain, niches that maintain a source of neural stem cells (NSCs) and neural progenitor cells (NPCs) are the subventricular zone (SVZ) of the lat...

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Detalles Bibliográficos
Autores principales: Aguirre, Adan, Rubio, Maria E., Gallo, Vittorio
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2941915/
https://www.ncbi.nlm.nih.gov/pubmed/20844536
http://dx.doi.org/10.1038/nature09347