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Ricin Toxin Activates the NALP3 Inflammasome

Ricin exhibits well characterized ribotoxic actions that lead to the inhibition of protein synthesis and the phosphorylation of stress activated protein kinases (SAPKs). Proinflammatory effects of ricin are thought to be caused by upregulation of genes encoding proinflammatory transcripts as a resul...

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Detalles Bibliográficos
Autores principales: Lindauer, Meghan, Wong, John, Magun, Bruce
Formato: Texto
Lenguaje:English
Publicado: MDPI 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2942780/
https://www.ncbi.nlm.nih.gov/pubmed/20862209
http://dx.doi.org/10.3390/toxins2061500