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Altered Metabolism and Persistent Starvation Behaviors Caused by Reduced AMPK Function in Drosophila
Organisms must utilize multiple mechanisms to maintain energetic homeostasis in the face of limited nutrient availability. One mechanism involves activation of the heterotrimeric AMP-activated protein kinase (AMPK), a cell-autonomous sensor to energetic changes regulated by ATP to AMP ratios. We exa...
Autores principales: | , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2942814/ https://www.ncbi.nlm.nih.gov/pubmed/20862213 http://dx.doi.org/10.1371/journal.pone.0012799 |