Altered Metabolism and Persistent Starvation Behaviors Caused by Reduced AMPK Function in Drosophila

Organisms must utilize multiple mechanisms to maintain energetic homeostasis in the face of limited nutrient availability. One mechanism involves activation of the heterotrimeric AMP-activated protein kinase (AMPK), a cell-autonomous sensor to energetic changes regulated by ATP to AMP ratios. We exa...

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Detalles Bibliográficos
Autores principales: Johnson, Erik C., Kazgan, Nevzat, Bretz, Colin A., Forsberg, Lawrence J., Hector, Clare E., Worthen, Ryan J., Onyenwoke, Rob, Brenman, Jay E.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2942814/
https://www.ncbi.nlm.nih.gov/pubmed/20862213
http://dx.doi.org/10.1371/journal.pone.0012799

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