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Combining ketamine with astrocytic inhibitor as a potential analgesic strategy for neuropathic pain. ketamine, astrocytic inhibitor and pain

BACKGROUND: Neuropathic pain is an intractable clinical problem. Intrathecal ketamine, a noncompetitive N--methyl-D-aspartate receptor (NMDAR) antagonist, is reported to be useful for treating neuropathic pain in clinic by inhibiting the activity of spinal neurons. Nevertheless, emerging studies hav...

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Detalles Bibliográficos
Autores principales: Mei, Xiao-Peng, Wang, Wei, Wang, Wen, Zhu, Chao, Chen, Lei, Zhang, Ting, Xu, Li-Xian, Wu, Sheng-Xi, Li, Yun-Qing
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2942826/
https://www.ncbi.nlm.nih.gov/pubmed/20815929
http://dx.doi.org/10.1186/1744-8069-6-50