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Intracellular Trafficking and Synaptic Function of APL-1 in Caenorhabditis elegans
BACKGROUND: Alzheimer's disease (AD) is a neurodegenerative disorder primarily characterized by the deposition of β-amyloid plaques in the brain. Plaques are composed of the amyloid-β peptide derived from cleavage of the amyloid precursor protein (APP). Mutations in APP lead to the development...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2010
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2942829/ https://www.ncbi.nlm.nih.gov/pubmed/20862215 http://dx.doi.org/10.1371/journal.pone.0012790 |