Distinct Epigenetic Domains Separated by a CTCF Bound Insulator between the Tandem Genes, BLU and RASSF1A

BACKGROUND: Tumor suppressor gene (TSG) RASSF1A and candidate TSG BLU are two tandem head-to-tail genes located at 3p21.3. We hypothesized that there may be a concordance on their gene expression and promoter methylation status. If not, then there may be an insulator located between RASSF1A and BLU...

Descripción completa

Detalles Bibliográficos
Autores principales: Chang, Jer-Wei, Hsu, Han-Shui, Ni, Huey-Juin, Chuang, Ching-Ting, Hsiung, Chi-Hui, Huang, Tim H., Wang, Yi-Ching
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2942851/
https://www.ncbi.nlm.nih.gov/pubmed/20877461
http://dx.doi.org/10.1371/journal.pone.0012847

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2942851/
https://www.ncbi.nlm.nih.gov/pubmed/20877461
http://dx.doi.org/10.1371/journal.pone.0012847

Ejemplares similares