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Migration, early axonogenesis, and Reelin-dependent layer-forming behavior of early/posterior-born Purkinje cells in the developing mouse lateral cerebellum

BACKGROUND: Cerebellar corticogenesis begins with the assembly of Purkinje cells into the Purkinje plate (PP) by embryonic day 14.5 (E14.5) in mice. Although the dependence of PP formation on the secreted protein Reelin is well known and a prevailing model suggests that Purkinje cells migrate along...

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Detalles Bibliográficos
Autores principales: Miyata, Takaki, Ono, Yuichi, Okamoto, Mayumi, Masaoka, Makoto, Sakakibara, Akira, Kawaguchi, Ayano, Hashimoto, Mitsuhiro, Ogawa, Masaharu
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2942860/
https://www.ncbi.nlm.nih.gov/pubmed/20809939
http://dx.doi.org/10.1186/1749-8104-5-23