siRNA-Based Targeting of Cyclin E Overexpression Inhibits Breast Cancer Cell Growth and Suppresses Tumor Development in Breast Cancer Mouse Model

Cyclin E is aberrantly expressed in many types of cancer including breast cancer. High levels of the full length as well as the low molecular weight isoforms of cyclin E are associated with poor prognosis of breast cancer patients. Notably, cyclin E overexpression is also correlated with triple-nega...

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Detalles Bibliográficos
Autores principales: Liang, Yulong, Gao, Hong, Lin, Shiaw-Yih, Goss, John A., Brunicardi, Francis C., Li, Kaiyi
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2942895/
https://www.ncbi.nlm.nih.gov/pubmed/20877462
http://dx.doi.org/10.1371/journal.pone.0012860

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2942895/
https://www.ncbi.nlm.nih.gov/pubmed/20877462
http://dx.doi.org/10.1371/journal.pone.0012860

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