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Podocyte-Specific Overexpression of Wild Type or Mutant Trpc6 in Mice Is Sufficient to Cause Glomerular Disease

Mutations in the TRPC6 calcium channel (Transient receptor potential channel 6) gene have been associated with familiar forms of Focal and Segmental Glomerulosclerosis (FSGS) affecting children and adults. In addition, acquired glomerular diseases are associated with increased expression levels of T...

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Detalles Bibliográficos
Autores principales: Krall, Paola, Canales, Cesar P., Kairath, Pamela, Carmona-Mora, Paulina, Molina, Jessica, Carpio, J. Daniel, Ruiz, Phillip, Mezzano, Sergio A., Li, Jing, Wei, Changli, Reiser, Jochen, Young, Juan I., Walz, Katherina
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2942896/
https://www.ncbi.nlm.nih.gov/pubmed/20877463
http://dx.doi.org/10.1371/journal.pone.0012859