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PPARγ Ligands Switched High Fat Diet-Induced Macrophage M2b Polarization toward M2a Thereby Improving Intestinal Candida Elimination

Obesity is associated with a chronic low-grade inflammation that predisposes to insulin resistance and the development of type 2 diabetes. In this metabolic context, gastrointestinal (GI) candidiasis is common. We recently demonstrated that the PPARγ ligand rosiglitazone promotes the clearance of Ca...

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Detalles Bibliográficos
Autores principales: Lefèvre, Lise, Galès, Amandine, Olagnier, David, Bernad, José, Perez, Laurence, Burcelin, Rémy, Valentin, Alexis, Auwerx, Johan, Pipy, Bernard, Coste, Agnès
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2942900/
https://www.ncbi.nlm.nih.gov/pubmed/20877467
http://dx.doi.org/10.1371/journal.pone.0012828