Cargando…

Base Sequence Context Effects on Nucleotide Excision Repair

Nucleotide excision repair (NER) plays a critical role in maintaining the integrity of the genome when damaged by bulky DNA lesions, since inefficient repair can cause mutations and human diseases notably cancer. The structural properties of DNA lesions that determine their relative susceptibilities...

Descripción completa

Detalles Bibliográficos
Autores principales: Cai, Yuqin, Patel, Dinshaw J., Broyde, Suse, Geacintov, Nicholas E.
Formato: Texto
Lenguaje:English
Publicado: SAGE-Hindawi Access to Research 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2943111/
https://www.ncbi.nlm.nih.gov/pubmed/20871811
http://dx.doi.org/10.4061/2010/174252