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Base Sequence Context Effects on Nucleotide Excision Repair
Nucleotide excision repair (NER) plays a critical role in maintaining the integrity of the genome when damaged by bulky DNA lesions, since inefficient repair can cause mutations and human diseases notably cancer. The structural properties of DNA lesions that determine their relative susceptibilities...
Autores principales: | Cai, Yuqin, Patel, Dinshaw J., Broyde, Suse, Geacintov, Nicholas E. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
SAGE-Hindawi Access to Research
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2943111/ https://www.ncbi.nlm.nih.gov/pubmed/20871811 http://dx.doi.org/10.4061/2010/174252 |
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