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MRI T2 Hypointensities in basal ganglia of premanifest Huntington's disease

Increased iron levels have been demonstrated in the basal ganglia of manifest Huntington’s disease (HD). An excess in iron accumulation correlates with MRI T2-weighted hypointensity. Determination of the amount of hypointensities in the basal ganglia in the premanifest phase of HD may give more insi...

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Detalles Bibliográficos
Autores principales: Jurgens, Caroline K, Jasinschi, Radu, Ekin, Ahmet, Witjes-Ané, Marie-Noëlle W, van der Grond, Jeroen, Middelkoop, Huub, Roos, Raymund A.C.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2943244/
https://www.ncbi.nlm.nih.gov/pubmed/20877453
http://dx.doi.org/10.1371/currents.RRN1173