In Vitro Bypass of the Major Malondialdehyde- and Base Propenal-Derived DNA Adduct by Human Y-family DNA Polymerases κ, ι, and Rev1

[Image: see text] 3-(2′-Deoxy-β-d-erythro-pentofuranosyl)pyrimido-[1,2-a]purin-10(3H)-one (M(1)dG) is the major adduct derived from the reaction of DNA with the lipid peroxidation product malondialdehyde and the DNA peroxidation product base propenal. M(1)dG is mutagenic in Escherichia coli and mamm...

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Detalles Bibliográficos
Autores principales: Maddukuri, Leena, Eoff, Robert L., Choi, Jeong-Yun, Rizzo, Carmelo J., Guengerich, F. Peter, Marnett, Lawrence J.
Formato: Texto
Lenguaje:English
Publicado: American Chemical Society 2010
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2943251/
https://www.ncbi.nlm.nih.gov/pubmed/20726503
http://dx.doi.org/10.1021/bi1009024

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2943251/
https://www.ncbi.nlm.nih.gov/pubmed/20726503
http://dx.doi.org/10.1021/bi1009024

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