Cargando…

In Vitro Bypass of the Major Malondialdehyde- and Base Propenal-Derived DNA Adduct by Human Y-family DNA Polymerases κ, ι, and Rev1

[Image: see text] 3-(2′-Deoxy-β-d-erythro-pentofuranosyl)pyrimido-[1,2-a]purin-10(3H)-one (M(1)dG) is the major adduct derived from the reaction of DNA with the lipid peroxidation product malondialdehyde and the DNA peroxidation product base propenal. M(1)dG is mutagenic in Escherichia coli and mamm...

Descripción completa

Detalles Bibliográficos
Autores principales:	Maddukuri, Leena, Eoff, Robert L., Choi, Jeong-Yun, Rizzo, Carmelo J., Guengerich, F. Peter, Marnett, Lawrence J.
Formato:	Texto
Lenguaje:	English
Publicado:	American Chemical Society 2010
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2943251/ https://www.ncbi.nlm.nih.gov/pubmed/20726503 http://dx.doi.org/10.1021/bi1009024

Ejemplares similares

Structural and Functional Analysis of Sulfolobus solfataricus Y-Family DNA Polymerase Dpo4-Catalyzed Bypass of the Malondialdehyde−Deoxyguanosine Adduct(,)
por: Eoff, Robert L., et al.
Publicado: (2009)

Human Rev1 polymerase disrupts G-quadruplex DNA
por: Eddy, Sarah, et al.
Publicado: (2014)

Translesion DNA Synthesis by Human DNA Polymerase η on Templates Containing a Pyrimidopurinone Deoxyguanosine Adduct, 3-(2′-Deoxy-β-d-erythro-pentofuranosyl)pyrimido-[1,2-a]purin-10(3H)-one
por: Stafford, Jennifer B., et al.
Publicado: (2008)

Rev1 promotes replication through UV lesions in conjunction with DNA polymerases η, ι, and κ but not DNA polymerase ζ
por: Yoon, Jung-Hoon, et al.
Publicado: (2015)

Biochemical Analysis of Six Genetic Variants of Error-Prone Human DNA Polymerase ι Involved in Translesion DNA Synthesis
por: Kim, Jinsook, et al.
Publicado: (2014)

Mechanistic Studies with DNA Polymerases Reveal Complex Outcomes following Bypass of DNA Damage
por: Eoff, Robert L., et al.
Publicado: (2010)

Translesion Synthesis of the N(2)-2′-Deoxyguanosine Adduct of the Dietary Mutagen IQ in Human Cells: Error-Free Replication by DNA Polymerase κ and Mutagenic Bypass by DNA Polymerases η, ζ, and Rev1
por: Bose, Arindam, et al.
Publicado: (2016)

Enzymatic bypass and the structural basis of miscoding opposite the DNA adduct 1,N(2)-ethenodeoxyguanosine by human DNA translesion polymerase η
por: Ghodke, Pratibha P., et al.
Publicado: (2021)

The Werner syndrome protein limits the error-prone 8-oxo-dG lesion bypass activity of human DNA polymerase kappa
por: Maddukuri, Leena, et al.
Publicado: (2014)

Identification and Characterization of Thermostable Y-Family DNA Polymerases η, ι, κ and Rev1 From a Lower Eukaryote, Thermomyces lanuginosus
por: Vaisman, Alexandra, et al.
Publicado: (2021)

Oxidation and Glycolytic Cleavage of Etheno and Propano DNA Base Adducts†
por: Knutson, Charles G., et al.
Publicado: (2009)

Posttranslational Regulation of Human DNA Polymerase ι
por: McIntyre, Justyna, et al.
Publicado: (2015)

Corrigendum: Identification and Characterization of Thermostable Y-Family DNA Polymerases η, ι, κ and Rev1 From a Lower Eukaryote, Thermomyces lanuginosus
por: Vaisman, Alexandra, et al.
Publicado: (2021)

Contiguous 2,2,4-triamino-5(2H)-oxazolone obstructs DNA synthesis by DNA polymerases α, β, η, ι, κ, REV1 and Klenow Fragment exo(−), but not by DNA polymerase ζ
por: Suzuki, Masayo, et al.
Publicado: (2016)

DNA polymerases η and κ bypass N(2)-guanine-O(6)-alkylguanine DNA alkyltransferase cross-linked DNA-peptides
por: Ghodke, Pratibha P., et al.
Publicado: (2021)

Bypass of DNA interstrand crosslinks by a Rev1–DNA polymerase ζ complex
por: Bezalel-Buch, Rachel, et al.
Publicado: (2020)

Mechanism of Repair of Acrolein- and Malondialdehyde-Derived Exocyclic Guanine Adducts by the α-Ketoglutarate/Fe(II) Dioxygenase AlkB
por: Singh, Vipender, et al.
Publicado: (2014)

DNA polymerase ι is acetylated in response to S(N)2 alkylating agents
por: McIntyre, Justyna, et al.
Publicado: (2019)

Replication Bypass of the trans-4-Hydroxynonenal-Derived (6S,8R,11S)-1,N(2)-Deoxyguanosine DNA Adduct by the Sulfolobus solfataricus DNA Polymerase IV
por: Banerjee, Surajit, et al.
Publicado: (2012)

Etheno adducts: from tRNA modifications to DNA adducts and back to miscoding ribonucleotides
por: Guengerich, F. Peter, et al.
Publicado: (2021)

DNA polymerases ζ and Rev1 mediate error-prone bypass of non-B DNA structures
por: Northam, Matthew R., et al.
Publicado: (2014)

Bypass of Aflatoxin B(1) Adducts by the Sulfolobus solfataricus DNA Polymerase IV
por: Banerjee, Surajit, et al.
Publicado: (2011)

Ring-Opening of the γ-OH-PdG Adduct Promotes Error-Free Bypass by the Sulfolobus solfataricus DNA Polymerase Dpo4
por: Shanmugam, Ganesh, et al.
Publicado: (2013)

The Steric Gate of DNA Polymerase ι Regulates Ribonucleotide Incorporation and Deoxyribonucleotide Fidelity
por: Donigan, Katherine A., et al.
Publicado: (2014)

Structure of the 1,N(2)-Ethenodeoxyguanosine Adduct Opposite Cytosine in Duplex DNA: Hoogsteen Base Pairing at pH 5.2
por: Shanmugam, Ganesh, et al.
Publicado: (2008)

Ubiquitin mediates the physical and functional interaction between human DNA polymerases η and ι
por: McIntyre, Justyna, et al.
Publicado: (2013)

Arrest of human mitochondrial RNA polymerase transcription by the biological aldehyde adduct of DNA, M(1)dG
por: Cline, Susan D., et al.
Publicado: (2010)

Evolution of Rev7 interactions in eukaryotic TLS DNA polymerase Polζ
por: McPherson, Kerry Silva, et al.
Publicado: (2022)

The peroxidation-derived DNA adduct, 6-oxo-M(1)dG, is a strong block to replication by human DNA polymerase η
por: Richie-Jannetta, Robyn, et al.
Publicado: (2023)

Mechanism of error-free DNA synthesis across N1-methyl-deoxyadenosine by human DNA polymerase-ι
por: Jain, Rinku, et al.
Publicado: (2017)

DNA polymerases κ and ζ cooperatively perform mutagenic translesion synthesis of the C8–2′-deoxyguanosine adduct of the dietary mutagen IQ in human cells
por: Bose, Arindam, et al.
Publicado: (2015)

Activation of dihaloalkanes by glutathione conjugation and formation of DNA adducts.
por: Guengerich, F P, et al.
Publicado: (1987)

129-derived Strains of Mice Are Deficient in DNA Polymerase ι and Have Normal Immunoglobulin Hypermutation
por: McDonald, John P., et al.
Publicado: (2003)

DNA polymerase ι functions in the generation of tandem mutations during somatic hypermutation of antibody genes
por: Maul, Robert W., et al.
Publicado: (2016)

DNA polymerase iota (Pol ι) promotes invasion and metastasis of esophageal squamous cell carcinoma
por: Zou, Shitao, et al.
Publicado: (2016)

Protein Modification by Adenine Propenal
por: Shuck, Sarah C., et al.
Publicado: (2014)

Enzymatic bypass of an N(6)-deoxyadenosine DNA–ethylene dibromide–peptide cross-link by translesion DNA polymerases
por: Ghodke, Pratibha P., et al.
Publicado: (2021)

A Comprehensive Strategy to Discover Inhibitors of the Translesion Synthesis DNA Polymerase κ
por: Yamanaka, Kinrin, et al.
Publicado: (2012)

DNA Polymerase ι Interacts with Both the TRAF-like and UBL1-2 Domains of USP7
por: Ashton, Nicholas W., et al.
Publicado: (2020)

Polymerase iota (Pol ι) prevents PrimPol-mediated nascent DNA synthesis and chromosome instability
por: Mansilla, Sabrina F., et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_em98o8fha6g1edtr64qa4oe7fk