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Stochastic E2F Activation and Reconciliation of Phenomenological Cell-Cycle Models

The transition of the mammalian cell from quiescence to proliferation is a highly variable process. Over the last four decades, two lines of apparently contradictory, phenomenological models have been proposed to account for such temporal variability. These include various forms of the transition pr...

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Detalles Bibliográficos
Autores principales: Lee, Tae J., Yao, Guang, Bennett, Dorothy C., Nevins, Joseph R., You, Lingchong
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2943438/
https://www.ncbi.nlm.nih.gov/pubmed/20877711
http://dx.doi.org/10.1371/journal.pbio.1000488