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Genetic Variants in Nuclear-Encoded Mitochondrial Genes Influence AIDS Progression
BACKGROUND: The human mitochondrial genome includes only 13 coding genes while nuclear-encoded genes account for 99% of proteins responsible for mitochondrial morphology, redox regulation, and energetics. Mitochondrial pathogenesis occurs in HIV patients and genetically, mitochondrial DNA haplogroup...
Autores principales: | , , , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2943476/ https://www.ncbi.nlm.nih.gov/pubmed/20877624 http://dx.doi.org/10.1371/journal.pone.0012862 |