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Relationship of EMAST and Microsatellite Instability Among Patients with Rectal Cancer

BACKGROUND: Elevated microsatellite instability at selected tetranucleotide repeats (EMAST) is a genetic signature identified in 60% of sporadic colon cancers and may be linked with heterogeneous expression of the DNA mismatch repair (MMR) protein hMSH3. Unlike microsatellite instability-high (MSI-H...

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Detalles Bibliográficos
Autores principales: Devaraj, Bikash, Lee, Aaron, Cabrera, Betty L., Miyai, Katsumi, Luo, Linda, Ramamoorthy, Sonia, Keku, Temitope, Sandler, Robert S., McGuire, Kathleen L., Carethers, John M.
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2943582/
https://www.ncbi.nlm.nih.gov/pubmed/20844976
http://dx.doi.org/10.1007/s11605-010-1340-6