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A two-parameter generalized Poisson model to improve the analysis of RNA-seq data
Deep sequencing of RNAs (RNA-seq) has been a useful tool to characterize and quantify transcriptomes. However, there are significant challenges in the analysis of RNA-seq data, such as how to separate signals from sequencing bias and how to perform reasonable normalization. Here, we focus on a funda...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2010
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2943596/ https://www.ncbi.nlm.nih.gov/pubmed/20671027 http://dx.doi.org/10.1093/nar/gkq670 |