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Requirements for catalysis in the Cre recombinase active site

Members of the tyrosine recombinase (YR) family of site-specific recombinases catalyze DNA rearrangements using phosphoryl transfer chemistry that is identical to that used by the type IB topoisomerases (TopIBs). To better understand the requirements for YR catalysis and the relationship between the...

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Detalles Bibliográficos
Autores principales: Gibb, Bryan, Gupta, Kushol, Ghosh, Kaushik, Sharp, Robert, Chen, James, Van Duyne, Gregory D.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2943603/
https://www.ncbi.nlm.nih.gov/pubmed/20462863
http://dx.doi.org/10.1093/nar/gkq384