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The non-coding RNA TERRA is a natural ligand and direct inhibitor of human telomerase

Telomeres, the physical ends of eukaryotes chromosomes are transcribed into telomeric repeat containing RNA (TERRA), a large non-coding RNA of unknown function, which forms an integral part of telomeric heterochromatin. TERRA molecules resemble in sequence the telomeric DNA substrate as they contain...

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Detalles Bibliográficos
Autores principales: Redon, Sophie, Reichenbach, Patrick, Lingner, Joachim
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2943627/
https://www.ncbi.nlm.nih.gov/pubmed/20460456
http://dx.doi.org/10.1093/nar/gkq296