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Genomic tagging reveals a random association of endogenous PtdIns5P 4-kinases IIα and IIβ and a partial nuclear localization of the IIα isoform

PtdIns5P 4-kinases IIα and IIβ are cytosolic and nuclear respectively when transfected into cells, including DT40 cells [Richardson, Wang, Clarke, Patel and Irvine (2007) Cell. Signalling 19, 1309–1314]. In the present study we have genomically tagged both type II PtdIns5P 4-kinase isoforms in DT40...

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Detalles Bibliográficos
Autores principales: Wang, Minchuan, Bond, Nicholas J., Letcher, Andrew J., Richardson, Jonathan P., Lilley, Kathryn S., Irvine, Robin F., Clarke, Jonathan H.
Formato: Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2943749/
https://www.ncbi.nlm.nih.gov/pubmed/20569199
http://dx.doi.org/10.1042/BJ20100340