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A calcineurin/AKAP complex is required for NMDA receptor-dependent LTD
AKAP79/150 is a protein scaffold thought to position specific kinases (PKA, PKC) and phosphastases (calcineurin) in appropriate synaptic domains so that their activities can regulate excitatory synaptic strength. Using a viral-mediated molecular replacement strategy in rat hippocampal slices, we fou...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2943866/ https://www.ncbi.nlm.nih.gov/pubmed/20694001 http://dx.doi.org/10.1038/nn.2613 |