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A Mouse Strain Where Basal Connective Tissue Growth Factor Gene Expression Can Be Switched from Low to High
Connective tissue growth factor (CTGF) is a signaling molecule that primarily functions in extracellular matrix maintenance and repair. Increased Ctgf expression is associated with fibrosis in chronic organ injury. Studying the role of CTGF in fibrotic disease in vivo, however, has been hampered by...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2943916/ https://www.ncbi.nlm.nih.gov/pubmed/20877562 http://dx.doi.org/10.1371/journal.pone.0012909 |