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A Mouse Strain Where Basal Connective Tissue Growth Factor Gene Expression Can Be Switched from Low to High

Connective tissue growth factor (CTGF) is a signaling molecule that primarily functions in extracellular matrix maintenance and repair. Increased Ctgf expression is associated with fibrosis in chronic organ injury. Studying the role of CTGF in fibrotic disease in vivo, however, has been hampered by...

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Detalles Bibliográficos
Autores principales: Doherty, Heather E., Kim, Hyung-Suk, Hiller, Sylvia, Sulik, Kathleen K., Maeda, Nobuyo
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2943916/
https://www.ncbi.nlm.nih.gov/pubmed/20877562
http://dx.doi.org/10.1371/journal.pone.0012909