Green Tea Catechin, Epigallocatechin Gallate, Suppresses Signaling by the dsRNA Innate Immune Receptor RIG-I

BACKGROUND: The Innate immune system constitutes the first line of defense against pathogen infections. The Retinoic acid-inducible gene I (RIG-I) receptor recognizes triphosphorylated ssRNAs and dsRNA to initiate downstream signaling of interferon response. However, unregulated activity of these re...

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Detalles Bibliográficos
Autores principales: Ranjith-Kumar, C. T., Lai, Yvonne, Sarisky, Robert T., Cheng Kao, C.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2943919/
https://www.ncbi.nlm.nih.gov/pubmed/20877565
http://dx.doi.org/10.1371/journal.pone.0012878

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2943919/
https://www.ncbi.nlm.nih.gov/pubmed/20877565
http://dx.doi.org/10.1371/journal.pone.0012878

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