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Human Integrin α(3)β(1) Regulates TLR2 Recognition of Lipopeptides from Endosomal Compartments

BACKGROUND: Toll-like receptor (TLR)-2/TLR1 heterodimers recognize bacterial lipopeptides and initiate the production of inflammatory mediators. Adaptors and co-receptors that mediate this process, as well as the mechanisms by which these adaptors and co-receptors function, are still being discovere...

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Detalles Bibliográficos
Autores principales: Marre, Meghan L., Petnicki-Ocwieja, Tanja, DeFrancesco, Alicia S., Darcy, Courtney T., Hu, Linden T.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2943923/
https://www.ncbi.nlm.nih.gov/pubmed/20877569
http://dx.doi.org/10.1371/journal.pone.0012871