Substitution of adeno-associated virus Rep protein binding and nicking sites with human Chromosome 19 sequences

BACKGROUND: Adeno-associated virus type 2 (AAV2) preferentially integrates its DNA at a ~2 kb region of human chromosome 19, designated AAVS1 (also known as MBS85). Integration at AAVS1 requires the AAV2 replication (Rep) proteins and a DNA sequence within AAVS1 containing a 16 bp Rep recognition se...

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Detalles Bibliográficos
Autores principales: McAlister, Victor J, Owens, Roland A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2944168/
https://www.ncbi.nlm.nih.gov/pubmed/20825662
http://dx.doi.org/10.1186/1743-422X-7-218

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2944168/
https://www.ncbi.nlm.nih.gov/pubmed/20825662
http://dx.doi.org/10.1186/1743-422X-7-218

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