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Synergism in hyperhomocysteinemia and diabetes: role of PPAR gamma and tempol

BACKGROUND: Hyperhomocysteinemia (HHcy) and hyperglycemia cause diabetic cardiomyopathy by inducing oxidative stress and attenuating peroxisome proliferator- activated receptor (PPAR) gamma. However, their synergistic contribution is not clear. METHODS: Diabetic Akita (Ins2+/-) and hyperhomocysteine...

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Detalles Bibliográficos
Autores principales: Mishra, Paras K, Tyagi, Neetu, Sen, Utpal, Joshua, Irving G, Tyagi, Suresh C
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2944245/
https://www.ncbi.nlm.nih.gov/pubmed/20828387
http://dx.doi.org/10.1186/1475-2840-9-49