Phospholemman Ser69 phosphorylation contributes to sildenafil-induced cardioprotection against reperfusion injury

The phosphodiesterase type-5 inhibitor sildenafil has powerful cardioprotective effects against ischemia-reperfusion injury. PKG-mediated signaling has been implicated in this protection, although the mechanism and the downstream targets of this kinase remain to be fully elucidated. In this study we...

Descripción completa

Detalles Bibliográficos
Autores principales: Madhani, Melanie, Hall, Andrew R., Cuello, Friederike, Charles, Rebecca L., Burgoyne, Joseph R., Fuller, William, Hobbs, Adrian J., Shattock, Michael J., Eaton, Philip
Formato: Texto
Lenguaje:English
Publicado: American Physiological Society 2010
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2944484/
https://www.ncbi.nlm.nih.gov/pubmed/20543084
http://dx.doi.org/10.1152/ajpheart.00129.2010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2944484/
https://www.ncbi.nlm.nih.gov/pubmed/20543084
http://dx.doi.org/10.1152/ajpheart.00129.2010

Ejemplares similares