Loss of Maternal ATRX Results in Centromere Instability and Aneuploidy in the Mammalian Oocyte and Pre-Implantation Embryo

The α-thalassemia/mental retardation X-linked protein (ATRX) is a chromatin-remodeling factor known to regulate DNA methylation at repetitive sequences of the human genome. We have previously demonstrated that ATRX binds to pericentric heterochromatin domains in mouse oocytes at the metaphase II sta...

Descripción completa

Detalles Bibliográficos
Autores principales: Baumann, Claudia, Viveiros, Maria M., De La Fuente, Rabindranath
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2944790/
https://www.ncbi.nlm.nih.gov/pubmed/20885787
http://dx.doi.org/10.1371/journal.pgen.1001137

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2944790/
https://www.ncbi.nlm.nih.gov/pubmed/20885787
http://dx.doi.org/10.1371/journal.pgen.1001137

Ejemplares similares